| San Roque Department | |
| Native Name: | Departamento San Roque |
| Settlement Type: | Department |
| Coordinates: | -28.5667°N -101°W |
| Subdivision Type: | Country |
| Subdivision Name: | Argentina |
| Established Title: | Established |
| Seat Type: | Seat |
| Seat: | San Roque |
| Leader Title: | Mayor |
| Unit Pref: | Metric |
| Area Total Km2: | 2,243 |
| Population Total: | 17,951 |
| Population Density Km2: | auto |
| Postal Code Type: | Postal Code |
| Postal Code: | W3448 |
| Area Code Type: | Area Code |
| Area Code: | 03777 |
San Roque Department is a department of Corrientes Province in Argentina.
The provincial subdivision has a population of about 17,951 inhabitants in an area of, its capital city is San Roque.