| San Rafael | |
| Settlement Type: | Municipality and town |
| Mapsize: | 250px |
| Pushpin Map: | Colombia |
| Pushpin Mapsize: | 250 |
| Pushpin Map Caption: | Location in Colombia |
| Subdivision Type: | Country |
| Subdivision Type1: | Department |
| Subdivision Name1: | Antioquia Department |
| Subdivision Type2: | Subregion |
| Subdivision Name2: | Eastern |
| Area Footnotes: | [1] |
| Area Total Km2: | 362 |
| Population As Of: | Census 2018[2] |
| Population Total: | 12578 |
| Coordinates: | 6.295°N -75.0281°W |
| Timezone: | Colombia Standard Time |
| Utc Offset: | -5 |
San Rafael is a town and municipality in Antioquia Department, Colombia. Part of the subregion of Eastern Antioquia.
The town was founded in 1864 by a group of miners who were attracted to the abundance of gold in the region.[3] It is also rich in water resources. The population was 12,578 at the 2018 census.