| San Nicolò d'Arcidano | |
| Official Name: | Comune di San Nicolò d'Arcidano |
| Native Name: | Arcidanu |
| Pushpin Map: | Italy Sardinia |
| Coordinates: | 39.6833°N 47°W |
| Region: | Sardinia |
| Province: | Oristano (OR) |
| Mayor: | Emanuele Cera |
| Area Total Km2: | 28.4 |
| Population Footnotes: | [1] |
| Population Total: | 2912 |
| Population As Of: | 2007 |
| Population Demonym: | Arcidanesi |
| Postal Code: | 09097 |
| Area Code: | 0783 |
San Nicolò d'Arcidano (Sardinian: Arcidànu) is a comune (municipality) in the Province of Oristano in the Italian region Sardinia, located about 70 km northwest of Cagliari and about 25 km south of Oristano.
San Nicolò d'Arcidano borders the following municipalities: Guspini, Mogoro, Pabillonis, Terralba, Uras.