| San Mateo Sindihui | |
| Settlement Type: | Municipality and town |
| Pushpin Map: | Mexico#North America |
| Pushpin Label Position: | above |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Oaxaca |
| Area Total Km2: | 181.17 |
| Population As Of: | 2000 |
| Population Total: | 1945 |
| Timezone: | Central Standard Time |
| Utc Offset: | -6 |
| Timezone Dst: | Central Daylight Time |
| Utc Offset Dst: | -5 |
| Coordinates: | 17°N -118°W |
San Mateo Sindihui is a town and municipality in Oaxaca in south-western Mexico. The municipality covers an area of 181.17 km². It is part of the Nochixtlán District in the southeast of the Mixteca Region.
As of 2005, the municipality had a total population of 1,945.[1]