| Official Name: | San Marcos de la Sierra |
| Pushpin Map: | Honduras |
| Pushpin Label Position: | right |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Honduras |
| Subdivision Type: | Country |
| Subdivision Name: | Honduras |
| Subdivision Type1: | Department |
| Subdivision Name1: | Intibucá |
| Area Total Km2: | 144 |
| Population As Of: | 2015 |
| Settlement Type: | Municipality |
| Population Total: | 8960 |
| Population Density Km2: | auto |
| Blank Name Sec1: | Municipality number |
| Blank Info Sec1: | 1013 |
| Coordinates: | 14.1167°N -103°W |
| Postal Code Type: | Postal code |
| Postal Code: | 14000 |
San Marcos de la Sierra is a municipality in the Honduran department of Intibucá.
At the time of the 2013 Honduras census, San Marcos de la Sierra municipality had a population of 8,653. Of these, 91.86% were Indigenous (91.74% Lenca), 7.96% Mestizo, 0.16% Black or Afro-Honduran and 0.02% White.[1]