| San Marco la Catola | |
| Official Name: | Comune di San Marco la Catola |
| Coordinates: | 41.5833°N 72°W |
| Region: | Apulia |
| Province: | (FG) |
| Mayor: | Luigi Piacquadio |
| Area Total Km2: | 28.63 |
| Population Footnotes: | [1] |
| Population Total: | 965 |
| Population As Of: | 31 December 2017 |
| Population Demonym: | Sammarchesi |
| Elevation M: | 686 |
| Saint: | St. Liberatus Martyr |
| Day: | 19 August |
| Postal Code: | 71030 |
| Area Code: | 0881 |
San Marco la Catola is a town and comune in the province of Foggia in the Apulia region of southeast Italy.
It is a small town built around an ancient medieval castle that still resides in the center of town. The castle has been inhabited by various monarchical leaders in the past, although it is associated most with Duke Pignatelli.The town has a rich history going back to at least the 12th century. It was originally a frontier fort, but over the years a small town was built around it.
Sights include the castle (now in ruins), perhaps dating to the 13th century, and the Sanctuary of the Madonna of Josafat (16th century).