| San Luis Amatlán | |
| Settlement Type: | Municipality and town |
| Pushpin Map: | Mexico |
| Pushpin Label Position: | above |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Oaxaca |
| Area Total Km2: | 170.96 |
| Population As Of: | 2005 |
| Population Total: | 3393 |
| Timezone: | Central Standard Time |
| Utc Offset: | -6 |
| Timezone Dst: | Central Daylight Time |
| Utc Offset Dst: | -5 |
| Coordinates: | 16.3833°N -126°W |
San Luis Amatlán is a town and municipality in Oaxaca in south-western Mexico. The municipality covers an area of 170.96 km2. It is part of the Miahuatlán District in the south of the Sierra Sur Region.
As of 2005, the municipality had a total population of 3,393.[1]