| Official Name: | San Luis |
| Settlement Type: | Municipality |
| Subdivision Type: | Country |
| Subdivision Name: | Cuba |
| Subdivision Type1: | Province |
| Subdivision Name1: | Pinar del Río |
| Established Title: | Founded |
| Established Date: | 1827 |
| Established Title2: | Established |
| Established Date2: | 1879 |
| Area Total Km2: | 765 |
| Population As Of: | 2022 |
| Population Total: | 31,242 |
| Population Density Km2: | auto |
| Timezone: | EST |
| Utc Offset: | -5 |
| Coordinates: | 22.2828°N -83.7681°W |
| Elevation M: | 25 |
| Area Code: | +53-82 |
San Luis is a municipality and town in the Pinar del Río Province of Cuba. It is centered mainly on agriculture (tobacco, rice, fruit crops), stock raising.
It was founded in 1827, and established as a municipality in 1879, when it split from San Juan y Martínez. Until 1977, its territory included the seaport village of La Coloma, currently part of Pinar del Río.[1]
The municipality is located west of Pinar del Río and includes the villages of Barbacoa, Barrigonas, Buenavista, El Corojo, El Retiro, Llanadas, Palizada, Santa María and Tirado.[2]
In 2022, the municipality of San Luis had a population of 31,242.[3] With a total area of 765km2,[4] it has a population density of 41/km2.