| San Lorenzo District | |
| Mapsize: | 300px |
| Pushpin Map: | Panama |
| Pushpin Label Position: | right |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location of the district capital in Panama |
| Subdivision Type: | Country |
| Subdivision Name: |  Panama |
| Subdivision Type1: | Province |
| Subdivision Name1: | Chiriquí Province |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Horconcitos |
| Unit Pref: | Imperial |
| Area Total Km2: | 738 |
| Population As Of: | 2000 |
| Population Total: | 6,498 |
| Population Blank1 Title: | Ethnicities |
| Timezone: | ETZ |
| Utc Offset: | -5 |
| Coordinates: | 8.32°N -82.16°W |
San Lorenzo District (pronounced as /es/) is a district (distrito) of Chiriquí Province in Panama. The population according to the 2000 census was 6,498.[1] The district covers a total area of 738 km2. The capital lies at the city of Horconcitos.[1]
San Lorenzo District is divided administratively into the following corregimientos: