| San Lorenzo Axocomanitla | |
| Settlement Type: | Municipality |
| Pushpin Map: | Mexico Tlaxcala#Mexico |
| Pushpin Label Position: | above |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Tlaxcala |
| Subdivision Type2: | Capital |
| Subdivision Name2: | San Lorenzo Axocomanitla |
| Leader Title: | Mayor |
| Leader Name: | Oracio Tuxpan Sánchez |
| Area Total Km2: | 4,540 |
| Population As Of: | 2005 |
| Population Total: | 5,045 |
| Population Density Km2: | auto |
| Timezone: | Central |
| Utc Offset: | -6 |
| Coordinates: | 19.2333°N -98.25°W |
San Lorenzo Axocomanitla is a town and its surrounding municipality in the Mexican state of Tlaxcala.[1] The municipality covers an area of 4,540 km2. The municipality has a total population of 5,045.