| San Leone I | |
| Other Name: | St. Leo I S. Leonis I Papæ |
| Mapframe: | yes |
| Mapframe-Caption: | Click on the map for a fullscreen view |
| Mapframe-Zoom: | 11 |
| Mapframe-Marker: | religious-christian |
| Coordinates: | 41.8909°N 12.5293°W |
| Location: | Via Prenestina 104, Rome |
| Country: | Italy |
| Denomination: | Roman Catholic |
| Tradition: | Roman Rite |
| Cardinal Protector: | Cristóbal López Romero |
| Dedication: | Pope Leo I |
| Consecration Year: | 1952 |
| Status: | Titular church |
| Architect: | Giuseppe Zander |
| Architectural Type: | Church |
| Groundbreaking: | 1950 |
| Completed Date: | 1952 |
The church of San Leone is a church of Rome in Prenestino-Labicano district, in via Prenestina. It is dedicated to the fifth-century pope, Pope Leo I.
The church was built by the architect Giuseppe Zander between 1950 and 1952.
It is the home of the parish, established 7 October 1952 by decree of the Cardinal Vicar Clemente Micara Tricesimo iam vertente. In addition it is also home since 1965 the title of cardinal "San Leone I".
The church was visited by Pope John Paul II 17 December 1989.[1]