| Official Name: | San José |
| Pushpin Map: | Argentina |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Argentina |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Name1: | Catamarca |
| Subdivision Type2: | Department |
| Subdivision Name2: | Fray Mamerto Esquiú |
| Subdivision Type3: | 2nd level Municipality |
| Subdivision Name3: | San José |
| Population Total: | 2,064 |
| Coordinates: | -28.3667°N -107°W |
| Elevation M: | 580 |
| Postal Code Type: | CPA Base |
| Postal Code: | K 4709 |
| Area Code: | +54 3833 |
| Timezone: | ART |
| Utc Offset: | -3 |
San José de Fray Mamerto Esquiú or simply San José is a town in Catamarca Province, Argentina. It is the head town of the Fray Mamerto Esquiú Department. It is part of the Gran San Fernando del Valle de Catamarca urban agglomeration.