| Official Name: | San Isidro |
| Pushpin Map: | Honduras |
| Pushpin Label Position: | left |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Honduras |
| Subdivision Type: | Country |
| Subdivision Name: | Honduras |
| Subdivision Type1: | Department |
| Subdivision Name1: | Choluteca |
| Population As Of: | 2015 |
| Population Footnotes: | [1] |
| Settlement Type: | Municipality |
| Population Total: | 3721 |
| Coordinates: | 13.6333°N -105°W |
| Area Code: | 0613 |
San Isidro (pronounced as /es/) is a municipality in the Honduran department of Choluteca.[2]