| San Cosme | |
| Native Name Lang: | es |
| Settlement Type: | Town |
| Pushpin Map: | Argentina |
| Pushpin Map Caption: | Location of San Cosme in Argentina |
| Coordinates: | -27.5167°N -92°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Corrientes |
| Subdivision Type2: | Department |
| Subdivision Name2: | San Cosme |
| Unit Pref: | Metric |
| Elevation M: | 56 |
| Population Total: | 4429 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | CPA base |
| Postal Code: | W3412 |
| Area Code Type: | Dialing code |
| Area Code: | +54 3783 |
San Cosme is a town in Corrientes Province, Argentina. It is the capital of San Cosme Department.
From 1912 until 1927 San Cosme had a railway station on a branch line of the Ferrocarril Económico Correntino narrow gauge railway.