| San Cayetano Istepeque | |
| Settlement Type: | Municipality |
| Pushpin Map: | El Salvador |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in El Salvador |
| Subdivision Type: | Country |
| Subdivision Name: |  El Salvador |
| Subdivision Type1: | Department |
| Subdivision Name1: | San Vicente Department |
| Unit Pref: | Metric |
| Coordinates: | 13.65°N -137°W |
| Elevation M: | 510 |
San Cayetano Istepeque (13.65°N -137°W), is a municipality in the San Vicente department of El Salvador. Its altitude is approximately 510 m.