| Samuel Walter Willet Pickup | |
| Constituency Mp: | Annapolis |
| Parliament: | Canadian |
| Predecessor: | Fletcher Bath Wade |
| Successor: | Avard Longley Davidson |
| Term Start: | 1904 |
| Term End: | 1911 |
| Office2: | Member of the Legislative Council of Nova Scotia |
| Term Start2: | 1913 |
| Term End2: | 1928 |
| Birth Date: | 1 March 1859 |
| Birth Place: | Granville Ferry, Nova Scotia |
| Party: | Liberal |
Samuel Walter Willet Pickup (March 1, 1859 - November 15, 1935) was a Canadian farmer, merchant, shipbuilder, shipowner, and politician.
Born in Granville Ferry, Annapolis County, Nova Scotia, the son of Samuel Pickup, of English Loyalist descent, and Cyline G. Willett Pickup, his wife, of French Huguenot Loyalist descent, Pickup was educated in the Common Schools and at Mount Allison College (now Mount Allison University) in Sackville, New Brunswick. A merchant, farmer, shipbuilder, and shipowner, Pickup was a member of the Municipal Council for Annapolis County for eighteen years, during three years of which he was Warden of the County. He was elected to the House of Commons of Canada for the electoral district of Annapolis in the 1904 federal election. A Liberal, he was re-elected in 1908 and was defeated in 1911. He was defeated again in the 1930 federal election. In 1913, he was appointed to the Legislative Council of Nova Scotia, which was abolished in 1928.