Samuel Genersich (February 15, 1768 in Kežmarok - September 2, 1844 in Levoča) was a Carpathian German physician and botanist.
He was the son of Christian Genersich, merchant in Kežmarok, and his wife Anna Susanna born Royko. He was the younger brother of Johann Genersich, professor at the lyceum in Kežmarok and of Christian Genersich, a Lutheran pastor there.
Genersich studied in Kežmarok and graduated in medicine in Vienna. He practiced medicine for six years in Kežmarok, and was subsequently appointed municipal physician in Levoča. In this capacity he published the Belehrung in 1839.
In botany he published his Elenchus in 1798 and the Catalogus in 1801. A manuscript for a Flora Scepusiaca remains unpublished.
He collaborated with Göran Wahlenberg on his work about the plant taxonomy and geography of the High Tatras. Genersich was also in intensive contact with Pál Kitaibel. Kitaibel's herbarium at the Hungarian National Museum in Budapest contains many plants collected by Genersich.
He was married to Johanna Fabritzy and had six children. Samuel Genersich was an honorary member of the Botanical Society of Regensburg.
The genus Genersichia (Cyperaceae) was named for him by János Heuffel, as was Dianthus genersichii Gyorffy (Caryophyllaceae).