| Samuel Desjardins | |
| Smallimage: | Samuel Desjardins.jpg |
| Constituency Mp: | Terrebonne |
| Parliament: | Canadian |
| Predecessor: | Raymond Préfontaine |
| Successor: | Wilfrid Bruno Nantel |
| Term Start: | 1903 |
| Term End: | 1908 |
| Birth Date: | 25 July 1852 |
| Birth Place: | Ste-Thérèse, Canada East |
| Party: | Liberal |
Samuel Desjardins (July 25, 1852 - December 4, 1924) was a Canadian politician.
Born in Ste-Thérèse, Canada East, the son of Samuel Desjardins and Sophie Laurier, Desjardins was educated at the College of Ste-Thérèse de Blainville. A physician, He was first elected to the House of Commons of Canada for the electoral district of Terrebonne in a 1903 by-election held to fill the vacancy caused by Raymond Préfontaine choosing to sit for the riding of Maisonneuve, after having been elected in the two constituencies. A Liberal, he was re-elected at the general elections of 1904 and was defeated in 1908.