| Sampson Jackson II | |
| State Senate: | Mississippi State |
| State: | Mississippi |
| District: | 32nd |
| Term Start: | January 7, 1992 |
| Term End: | June 30, 2021 |
| Preceded: | Eddie Briggs |
| Succeeded: | Rod Hickman |
| Party: | Democratic |
| Birth Date: | 30 January 1953 |
| Birth Place: | Preston, Mississippi, U.S. |
| Occupation: | Businessman, farmer |
| Spouse: | Patricia Diane Hayes |
| Residence: | Dekalb, Mississippi |
Sampson Jackson II (born January 30, 1953) was a Democratic member of the Mississippi Senate who represented the 32nd District from 1992 until his resignation in 2021.[1] He was succeeded by Rod Hickman following a 2021 special election.[2]