| Samos Prefecture | |
| Native Name: | Νομός Σάμου |
| Settlement Type: | Former prefecture |
| Image Map1: | Samos municipalities numbered.png |
| Map Caption1: | Location of municipalities within Samos Prefecture Prefecture |
| Subdivision Type: | Country |
| Subdivision Name: | Greece |
| Subdivision Type1: | Periphery |
| Parts Type: | Subdivisions |
| P1: | 2 provinces |
| P2: | 8 municipalities |
| P3: | 0 communities |
| Seat Type: | Capital |
| Seat: | Vathy |
| Unit Pref: | Metric |
| Area Total Km2: | 778 |
| Area Rank: | 50th |
| Population Total: | 44114 |
| Population As Of: | 2005 |
| Population Density Km2: | auto |
| Population Density Rank: | 25th |
| Population Rank: | 49th |
| Postal Code Type: | Postal codes |
| Postal Code: | 83x xx |
| Area Code Type: | Area codes |
| Area Code: | 227x0 |
| Iso Code: | GR-84 |
| Registration Plate: | ΜΟ |
| Website: | www.samos.gr |
Samos Prefecture (el|Νομός Σάμου) was a prefecture in Greece, consisting of the islands of Samos, Ikaria and the smaller islands of Fournoi Korseon. In 2011 the prefecture was abolished and the territory is now covered by the regional units of Samos and Ikaria. Its capital was the town of Vathy, on Samos.
The provinces were:
| Municipality | Former Municipalities | YPES code | Seat (if different) | Postal code | Area code | |
|---|---|---|---|---|---|---|
| Icaria | 4601 | 833 00 | 22750-2 | |||
| 4603 | 833 02 | 22750-3 | ||||
| 4607 | 833 01 | 22750-4 | ||||
| Samos | Karlovasi | 4604 | 832 00 | 22730-3 | ||
| Marathokampos | 4605 | 831 02 | 22730-3 | |||
| Pythagoreio | 4606 | 831 03 | 22730-6 through 9 | |||
| 4602 | 831-00 | 22730-2 | ||||
| Fournoi Korseon | 4608 | Fournoi | 833 01 | 22750-5 | ||