| Sammy Holbrook | |
| Position: | Catcher |
| Bats: | Right |
| Throws: | Right |
| Birth Date: | July 17, 1910 |
| Birth Place: | Meridian, Mississippi |
| Death Place: | Jackson, Mississippi |
| Debutleague: | MLB |
| Debutdate: | April 25 |
| Debutyear: | 1935 |
| Debutteam: | Washington Senators |
| Finalleague: | MLB |
| Finaldate: | September 29 |
| Finalyear: | 1935 |
| Finalteam: | Washington Senators |
| Statleague: | MLB |
| Stat1label: | Batting average |
| Stat1value: | .259 |
| Stat2label: | Home runs |
| Stat2value: | 2 |
| Stat3label: | Runs batted in |
| Stat3value: | 25 |
| Teams: |
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James Marbury "Sammy" Holbrook (July 17, 1910 - April 10, 1991) was a Major League Baseball catcher. He played one season in the majors, in, for the Washington Senators. That year, he served as the primary backup to starting catcher Cliff Bolton.
Holbrook's minor league baseball career spanned 14 seasons, from until . In, he served as player-manager of the Federalsburg A's of the Eastern Shore League. Holbrook batted .361 in 98 games while leading the team to the league championship in his only season as manager.