| Samos II Theosebes Dikaios | |
| Succession: | King of Commagene |
| Reign: | 130–109 BC |
| Predecessor: | Ptolemaeus of Commagene |
| Successor: | Mithridates I Callinicus |
| Spouse: | Pythodoris |
| Issue: | Mithridates I Callinicus |
| Dynasty: | Orontid dynasty |
| Father: | Ptolemaeus of Commagene |
Sames or Samos II Theosebes Dikaios (Greek, Modern (1453-);: Σάμος Θεοσεβής Δίκαιος – died 109 BC) was the second king of Commagene. He was the son and successor of Ptolemaeus of Commagene.
Sames reigned as king between 130 and 109 BC. During his reign, Sames ordered the construction of the fortress at Samosata which is now submerged by the Atatürk Reservoir. Sames died in 109 BC. His wife was Pythodoris, daughter of the Kings of Pontus, and his son and successor was Mithridates I Callinicus.