| Samborombón River | |
| Mouth Location: | Samborombón Bay |
| Subdivision Type1: | Country |
| Subdivision Name1: | Argentina |
The Samborombón River (Spanish, Río Samborombón, literally "Saint Brendan River") is a river of Argentina. It empties into Samborombón Bay in the southern part of the Río de la Plata.