| Samé Diomgoma | |
| Settlement Type: | Commune and village |
| Pushpin Map: | Mali |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Mali |
| Subdivision Type: | Country |
| Subdivision Name: |  Mali |
| Subdivision Type1: | Region |
| Subdivision Name1: | Kayes Region |
| Subdivision Type2: | Cercle |
| Subdivision Name2: | Kayes Cercle |
| Population As Of: | 2009 |
| Population Footnotes: | [1] |
| Population Total: | 12820 |
| Population Blank1 Title: | Ethnicities |
| Utc Offset: | +0 |
| Coordinates: | 14.4833°N -45°W |
Samé or Samé Diomgoma is a village and commune in the Cercle of Kayes in the Kayes Region of south-western Mali. The commune includes 18 villages and lies to the south of the Senegal River. The Dakar-Niger Railway passes through Samé. In 2009 the commune had a population of 12,820.