Salicylate decarboxylase explained

Salicylate decarboxylase
Ec Number:	4.1.1.91

Salicylate decarboxylase (salicylic acid decarboxylase, Scd) is an enzyme with systematic name salicylate carboxy-lyase.^[1] This enzyme catalyses the following chemical reaction

\rightleftharpoons phenol + CO₂

In the reverse direction the enzyme catalyses the regioselective carboxylation of phenol into salicylate.

Notes and References

1. Kirimura K, Gunji H, Wakayama R, Hattori T, Ishii Y . Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase . Biochemical and Biophysical Research Communications . 394 . 2 . 279–84 . April 2010 . 20188702 . 10.1016/j.bbrc.2010.02.154 .