| Sainte-Séraphine | |
| Settlement Type: | Parish municipality |
| Pushpin Map: | Canada Southern Quebec |
| Pushpin Map Caption: | Location in southern Quebec. |
| Coordinates: | 45.9167°N -83°W |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Type2: | Region |
| Subdivision Name2: | Centre-du-Québec |
| Subdivision Type3: | RCM |
| Subdivision Name3: | Arthabaska |
| Established Title1: | Constituted |
| Established Date1: | March 7, 1931 |
| Leader Title: | Mayor |
| Leader Name: | Monique Paquin |
| Leader Title1: | Federal riding |
| Leader Name1: | Richmond—Arthabaska |
| Leader Title2: | Prov. riding |
| Leader Name2: | Drummond–Bois-Francs |
| Area Total Km2: | 76.20 |
| Area Land Km2: | 75.86 |
| Population Total: | 441 |
| Population As Of: | 2021 |
| Population Density Km2: | 5.8 |
| Population Blank1 Title: | Pop 2016-2021 |
| Population Blank1: | 24.2% |
| Timezone: | EST |
| Utc Offset: | −5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | −4 |
| Postal Code Type: | Postal code(s) |
| Postal Code: | J0A 1E0 |
| Area Code: | 819 |
| Blank Name: | Highways |
| Blank Info: | No major routes |
Sainte-Séraphine is a parish municipality located in the Centre-du-Québec region of Quebec, Canada.
In the 2021 Census of Population conducted by Statistics Canada, Sainte-Séraphine had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of 75.86km2, it had a population density of in 2021.[1]