| Sainte-Marie-en-Chaux | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Sainte-Marie-en-Chaux (Haute-Saône).svg |
| Coordinates: | 47.79°N 6.3131°W |
| Insee: | 70470 |
| Postal Code: | 70300 |
| Arrondissement: | Lure |
| Canton: | Saint-Loup-sur-Semouse |
| Mayor: | Pierre Duchanois[1] |
| Term: | 2020 - 2026 |
| Elevation Min M: | 247 |
| Elevation Max M: | 287 |
| Area Km2: | 2.43 |
Sainte-Marie-en-Chaux (in French pronounced as /sɛ̃t maʁi ɑ̃ ʃo/) is a commune in the Haute-Saône department in the region of Bourgogne-Franche-Comté in eastern France.