| Sainte-Hélène-sur-Isère | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Sainte-Hélène-sur-Isère 73.svg |
| Arrondissement: | Albertville |
| Canton: | Albertville-2 |
| Insee: | 73241 |
| Postal Code: | 73460 |
| Mayor: | Daniel Tavel[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CA Arlysère |
| Coordinates: | 45.6144°N 6.3217°W |
| Elevation Min M: | 298 |
| Elevation Max M: | 2294 |
| Area Km2: | 14.43 |
Sainte-Hélène-sur-Isère (in French pronounced as /sɛ̃t elɛn syʁ izɛʁ/, literally Sainte-Hélène on Isère) is a commune in the Savoie department in the Auvergne-Rhône-Alpes region in south-eastern France.