| Sainte-Gemme | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Sainte-Gemme (Tarn).svg |
| Arrondissement: | Albi |
| Canton: | Carmaux-1 Le Ségala |
| Insee: | 81249 |
| Postal Code: | 81190 |
| Mayor: | Jean-Claude Clergue[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Carmausin-Ségala |
| Coordinates: | 44.09°N 2.2011°W |
| Elevation M: | 344 |
| Elevation Min M: | 248 |
| Elevation Max M: | 394 |
| Area Km2: | 20.16 |
Sainte-Gemme (in French pronounced as /sɛ̃t ʒɛm/; Occitan (post 1500);: Santa Gèma) is a commune in the Tarn department in southern France.