| Sainte-Gemme | |
| Commune Status: | Commune |
| Arrondissement: | Langon |
| Canton: | Le Réolais et Les Bastides |
| Insee: | 33404 |
| Postal Code: | 33580 |
| Mayor: | Jean Claude Dubos[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 44.6211°N 0.0706°W |
| Elevation M: | 84 |
| Elevation Min M: | 30 |
| Elevation Max M: | 116 |
| Area Km2: | 9.55 |
Sainte-Gemme (in French pronounced as /sɛ̃t ʒɛm/; Occitan (post 1500);: Senta Gema) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France.