| Sainte-Colombe | |
| Commune Status: | Commune |
| Arrondissement: | Jonzac |
| Canton: | Les Trois Monts |
| Insee: | 17319 |
| Postal Code: | 17220 |
| Mayor: | Bernard Peruffo[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Haute-Saintonge |
| Coordinates: | 45.2839°N -0.2794°W |
| Elevation M: | 125 |
| Elevation Min M: | 75 |
| Elevation Max M: | 143 |
| Area Km2: | 4.38 |
Sainte-Colombe (pronounced as /fr/) is a commune in the Charente-Maritime department in the Nouvelle-Aquitaine region in southwestern France.
The Seugne forms most of the commune's southwestern border.