| Sainte-Colombe | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason de la ville de Sainte-Colombe (Yonne).svg |
| Coordinates: | 47.5672°N 3.97°W |
| Insee: | 89339 |
| Postal Code: | 89440 |
| Arrondissement: | Avallon |
| Canton: | Joux-la-Ville |
| Mayor: | Claude Catrin[1] |
| Term: | 2020 - 2026 |
| Elevation Min M: | 199 |
| Elevation Max M: | 361 |
| Area Km2: | 18.48 |
Sainte-Colombe (in French pronounced as /sɛ̃t kɔlɔ̃b/) is a commune in the Yonne department in Bourgogne-Franche-Comté in north-central France.