| Saint-Sernin | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-Sernin 11.svg |
| Arrondissement: | Carcassonne |
| Canton: | La Piège au Razès |
| Insee: | 11365 |
| Postal Code: | 11420 |
| Mayor: | Emilien Guilhemat[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 43.23°N 1.8°W |
| Elevation M: | 340 |
| Elevation Min M: | 271 |
| Elevation Max M: | 352 |
| Area Km2: | 6.53 |
Saint-Sernin (in French pronounced as /sɛ̃ sɛʁnɛ̃/; Occitan (post 1500);: Sant Sernin) is a commune in the Aude department in southern France.