| Saint-Sernin | |
| Commune Status: | Commune |
| Arrondissement: | Largentière |
| Canton: | Aubenas-2 |
| Insee: | 07296 |
| Postal Code: | 07200 |
| Mayor: | Max Chaze[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 44.5722°N 4.3925°W |
| Elevation M: | 186 |
| Elevation Min M: | 167 |
| Elevation Max M: | 365 |
| Area Km2: | 5.78 |
Saint-Sernin (in French pronounced as /sɛ̃ sɛʁnɛ̃/; Occitan (post 1500);: Sant Sarnin) is a commune in the Ardèche department in southern France.