| Saint-Paul-d'Espis | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-Paul-d'Espis (Tarn-et-Garonne).svg |
| Arrondissement: | Castelsarrasin |
| Canton: | Valence |
| Insee: | 82170 |
| Postal Code: | 82400 |
| Mayor: | Lido Marchiol[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Deux Rives |
| Coordinates: | 44.1447°N 0.9694°W |
| Elevation M: | 85 |
| Elevation Min M: | 68 |
| Elevation Max M: | 191 |
| Area Km2: | 26.07 |
Saint-Paul-d'Espis (Languedocien: Sent Pau dels Pins) is a commune in the Tarn-et-Garonne department in the Occitanie region in southern France.
The village lies on the left bank of the Barguelonne, which forms all of the commune's northwestern border.