| Saint-Mesmin | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason Saint-Mesmin.svg |
| Arrondissement: | Nontron |
| Canton: | Isle-Loue-Auvézère |
| Insee: | 24464 |
| Postal Code: | 24270 |
| Mayor: | Guy Bouchaud[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 45.3531°N 1.2061°W |
| Elevation M: | 300 |
| Elevation Min M: | 182 |
| Elevation Max M: | 415 |
| Area Km2: | 29.58 |
Saint-Mesmin (in French pronounced as /sɛ̃ mɛmɛ̃/; Limousin: Sent Maimin) is a commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France.
The commune is located in the north-east corner of the Dordogne department, on a hill above the river Auvézère. The village is located 42km (26miles) north-east of Périgueux. The area consists of forests and farmland.
From the creation of the departments in 1790 Saint-Mesmin was first included in the Corrèze department. Three years later in 1793 it joined the Dordogne department.
The largest population that the census recorded was 1,168 in 1886. Since World War I, the population has gradually been declining until it reached its lowest point in 2009.