| Saint-Mesmin | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-Mesmin (Côte-d'Or).svg |
| Arrondissement: | Montbard |
| Canton: | Semur-en-Auxois |
| Insee: | 21563 |
| Postal Code: | 21540 |
| Mayor: | Thierry Renault[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 47.3431°N 4.6536°W |
| Elevation M: | 490 |
| Elevation Min M: | 369 |
| Elevation Max M: | 561 |
| Area Km2: | 17.62 |
Saint-Mesmin (pronounced as /fr/) is a commune in the Côte-d'Or department in eastern France.