| Saint-Médard-de-Guizières | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-Médard-de-Guizières (Gironde).svg |
| Arrondissement: | Libourne |
| Canton: | Le Nord-Libournais |
| Insee: | 33447 |
| Postal Code: | 33230 |
| Mayor: | Mireille Conte Jaubert[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CA Libournais |
| Coordinates: | 45.0161°N -0.0578°W |
| Elevation M: | 16 |
| Elevation Min M: | 8 |
| Elevation Max M: | 67 |
| Area Km2: | 10.37 |
Saint-Médard-de-Guizières (pronounced as /fr/) is a commune in the Gironde department, region of Nouvelle-Aquitaine, southwestern France. It has been twinned with the village of Wedmore, England since 1975. Saint-Médard-de-Guizières station has rail connections to Bordeaux, Périgueux, Brive-la-Gaillarde and Limoges.