| Saint-Loup-en-Comminges | |
| Commune Status: | Commune |
| Arrondissement: | Saint-Gaudens |
| Canton: | Saint-Gaudens |
| Insee: | 31498 |
| Postal Code: | 31350 |
| Mayor: | Denis Bouzigues[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 43.2458°N 0.5839°W |
| Elevation M: | 420 |
| Elevation Min M: | 325 |
| Elevation Max M: | 466 |
| Area Km2: | 4.73 |
Saint-Loup-en-Comminges (pronounced as /fr/, literally Saint-Loup in Comminges; oc|Sent Lop de Comenge) is a commune in the Haute-Garonne department in southwestern France.
The river Gesse flows east-northeast through the southeastern part of the commune and forms part of its eastern border.