| Saint-Léon-sur-l'Isle | |
| Commune Status: | Commune |
| Arrondissement: | Périgueux |
| Canton: | Saint-Astier |
| Insee: | 24442 |
| Postal Code: | 24110 |
| Mayor: | Gérard Saurin[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Isle Vern Salembre en Périgord |
| Coordinates: | 45.1156°N 0.5053°W |
| Elevation M: | 73 |
| Elevation Min M: | 56 |
| Elevation Max M: | 192 |
| Area Km2: | 14.78 |
Saint-Léon-sur-l'Isle (in French pronounced as /sɛ̃ le.ɔ̃ syʁ lil/, literally Saint Léon on the Isle; Limousin: Sent Leu d’Eila) is a commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France. Saint-Léon-sur-l'Isle station has rail connections to Bordeaux, Périgueux, Brive-la-Gaillarde and Limoges.