| Saint-Guillaume | |
| Commune Status: | Commune |
| Arrondissement: | Grenoble |
| Canton: | Matheysine-Trièves |
| Insee: | 38391 |
| Postal Code: | 38650 |
| Mayor: | David Piccarreta[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Trièves |
| Coordinates: | 44.9558°N 5.5894°W |
| Elevation Min M: | 550 |
| Elevation Max M: | 1733 |
| Area Km2: | 13 |
Saint-Guillaume (in French pronounced as /sɛ̃ ɡijom/) is a commune in the Isère department in southeastern France.[2]