| Saint-Grégoire | |
| Native Name: | (Gallo) |
| Commune Status: | Commune |
| Coordinates: | 48.1517°N -1.685°W |
| Insee: | 35278 |
| Postal Code: | 35760 |
| Arrondissement: | Rennes |
| Canton: | Betton |
| Mayor: | Laëtitia Remoissenet[1] |
| Term: | 2024 - 2026 |
| Intercommunality: | Rennes Métropole |
| Elevation Min M: | 25 |
| Elevation Max M: | 92 |
| Area Km2: | 17.30 |
Saint-Grégoire (pronounced as /fr/; br|Sant-Gregor; Gallo: Saent-Gregoèrr) is a commune in the department of Ille-et-Vilaine, Brittany, northwestern France.
Inhabitants of Saint-Grégoire are called grégoriens in French.
The city hosts offices of important firms such as KPMG, or the "Banque Populaire Grand Ouest" and others well-known firms that make the commune important regarding the other communes around.