| Saint-Euphrône | |
| Commune Status: | Commune |
| Arrondissement: | Montbard |
| Canton: | Semur-en-Auxois |
| Insee: | 21547 |
| Postal Code: | 21140 |
| Mayor: | Benoist Boutier[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 47.4786°N 4.3811°W |
| Elevation M: | 303 |
| Elevation Min M: | 280 |
| Elevation Max M: | 351 |
| Area Km2: | 11.04 |
Saint-Euphrône (in French pronounced as /sɛ̃.t‿øfʁon/) is a commune in the Côte-d'Or department in eastern France.