| Saint-Barthélemy-de-Bussière | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-Barthélemy-de-Bussière (Dordogne).svg |
| Arrondissement: | Nontron |
| Canton: | Périgord Vert Nontronnais |
| Insee: | 24381 |
| Postal Code: | 24360 |
| Mayor: | Laurent Mollon[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 45.6414°N 0.7564°W |
| Elevation M: | 287 |
| Elevation Min M: | 218 |
| Elevation Max M: | 366 |
| Area Km2: | 15.01 |
Saint-Barthélemy-de-Bussière (in French pronounced as /sɛ̃ baʁtelemi də bysjɛʁ/, literally Saint-Barthélemy of Bussière; Occitan (post 1500);: Sent Bertomiu de Bussiera) is a commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France.