| Saint-Barthélemy | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-Barthélemy 70.svg |
| Coordinates: | 47.75°N 6.5889°W |
| Insee: | 70459 |
| Postal Code: | 70270 |
| Arrondissement: | Lure |
| Canton: | Mélisey |
| Mayor: | Francis Oudot[1] |
| Term: | 2020 - 2026 |
| Elevation Min M: | 324 |
| Elevation Max M: | 708 |
| Area Km2: | 13.46 |
Saint-Barthélemy (in French pronounced as /sɛ̃ baʁtelemi/) is a commune in the Haute-Saône department in the region of Bourgogne-Franche-Comté in eastern France.