| Saint-Antoine | |
| Commune Status: | Commune |
| Coordinates: | 46.7775°N 6.3383°W |
| Insee: | 25514 |
| Postal Code: | 25370 |
| Arrondissement: | Pontarlier |
| Canton: | Frasne |
| Mayor: | Brigitte Prêtre[1] |
| Term: | 2020 - 2026 |
| Elevation Min M: | 920 |
| Elevation Max M: | 1101 |
| Area Km2: | 4.51 |
Saint-Antoine (in French pronounced as /sɛ̃.t‿ɑ̃twan/) is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France.
The commune lies 12km (07miles) from Mouthe.
Saint-Antoine was earlier known as Rougebief after the stream that forms the boundary of the commune.