| Saint-André-et-Appelles | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Saint-André-et-Appelles (Gironde).svg |
| Arrondissement: | Libourne |
| Canton: | Le Réolais et Les Bastides |
| Insee: | 33369 |
| Postal Code: | 33220 |
| Mayor: | Éric Fréchou[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Pays Foyen |
| Coordinates: | 44.82°N 0.195°W |
| Elevation M: | 100 |
| Elevation Min M: | 7 |
| Elevation Max M: | 114 |
| Area Km2: | 10.25 |
Saint-André-et-Appelles (in French pronounced as /sɛ̃.t‿ɑ̃dʁe e apɛl/; Occitan (post 1500);: Sant Andrieu e Apèla) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France.