Saglin Explained

Saglin is a protein produced by the salivary glands of mosquitoes. It is thought that this protein allows the malarial sporozoite to bind to the salivary glands, allowing invasion.[1] It is currently under investigation as a potential drug target to help control transmission of the disease by controlling transmission in the vector.[2]

Notes and References

  1. Okulate et al. 2007 Identification and molecular characterization of a novel protein Saglin as a target of monoclonal antibodies affecting salivary gland infectivity of Plasmodium sporozoites
  2. The Saglin Project http://bioquest.org/oakwood2008/2008/08/this-is-the-saglin-project/

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