Saccharopolyspora spinosa explained

Saccharopolyspora spinosa is a species of actinobacterium first isolated from soil in a rum still in an abandoned sugar mill on the Virgin Islands. It was discovered and described by researchers Mertz and Yao while collecting specimens to be screened for novel antibiotics.^[1] It develops aerial, pale, yellowish pink hyphae and bears long chains of spores encased in spiny spore sheaths. It can also reproduce by fragmentation in an aqueous environment. Its type strain is A83543.1 (= NRRL 18395).

Saccharopolyspora spinosa is the source of a family of insecticidal compounds called spinosyns. They act as neurotoxins by activation of nicotinic acetylcholine receptors in insects. The insecticide Spinetoram is composed of two synthetic derivatives of spinosyns.^[2]

See also

• Spinosad

Further reading

• Pan. Y.. Yang. X.. Li. J.. Zhang. R.. Hu. Y.. Zhou. Y.. Wang. J.. Zhu. B.. Genome Sequence of the Spinosyns-Producing Bacterium Saccharopolyspora spinosa NRRL 18395. Journal of Bacteriology. 193. 12. 2011. 3150–3151. 0021-9193. 10.1128/JB.00344-11. 21478350. 3133185.
• Kim. Hak Joong. White-Phillip. Jess A.. Ogasawara. Yasushi. Shin. Nara. Isiorho. Eta A.. Liu. Hung-wen. Biosynthesis of Spinosyn in Saccharopolyspora spinosa: Synthesis of Permethylated Rhamnose and Characterization of the Functions of SpnH, SpnI, and SpnK. Journal of the American Chemical Society. 132. 9. 2010. 2901–2903. 0002-7863. 10.1021/ja910223x. 20158237. 2832084.
• Jin. Zhi-hua. Wu. Jian-ping. Zhang. Yuan. Cheng. Xiu. Yang. Li-rong. Cen. Pei-lin. Improvement of spinosad producing Saccharopolyspora spinosa by rational screening. Journal of Zhejiang University Science A. 7. S2. 2006. 366–370. 1009-3095. 10.1631/jzus.2006.AS0366. 122475979.

External links

• • Type strain of Saccharopolyspora spinosa at BacDive - the Bacterial Diversity Metadatabase

Notes and References

1. Mertz. F. P.. Yao. R. C.. Saccharopolyspora spinosa sp. nov. Isolated from Soil Collected in a Sugar Mill Rum Still. International Journal of Systematic Bacteriology. 40. 1. 1990. 34–39. 0020-7713. 10.1099/00207713-40-1-34. free.
2. Bacci L, Lupi D, Savoldelli S, Rossaro B . 28 April 2016 . A review of Spinosyns, a derivative of biological acting substances as a class of insecticides with a broad range of action against many insect pests . Journal of Entomological and Acarological Research . 48 . 1 . 40 . 10.4081/jear.2016.5653. 2279-7084 . free . 30 July 2022. 2434/380778 . free .