SYT9 explained

Synaptotagmin-9 is a protein that in humans is encoded by the SYT9 gene.^{[1] [2]}

Interactions

SYT9 has been shown to interact with SYNCRIP,^[3] TUBB^[4] and TRPV1.^[5]

Further reading

• Huda Zoghbi . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . Oct 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A . Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity . The Journal of Biological Chemistry . 279 . 24 . 25665–72 . Jun 2004 . 15066994 . 10.1074/jbc.M311515200 . free .
• Haberman Y, Grimberg E, Fukuda M, Sagi-Eisenberg R . Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules . Journal of Cell Science . 116 . Pt 21 . 4307–18 . Nov 2003 . 12966166 . 10.1242/jcs.00719 . free .

\* Dubois T, Howell S, Zemlickova E, Aitken A . Identification of casein kinase Ialpha interacting protein partners . FEBS Letters . 517 . 1–3 . 167–71 . Apr 2002 . 12062430 . 10.1016/S0014-5793(02)02614-5 . 84792445 . free .

• Zhang X, Kim-Miller MJ, Fukuda M, Kowalchyk JA, Martin TF . Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis . Neuron . 34 . 4 . 599–611 . May 2002 . 12062043 . 10.1016/S0896-6273(02)00671-2 . 16768299 . free .
• Fukuda M, Kowalchyk JA, Zhang X, Martin TF, Mikoshiba K . Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells . The Journal of Biological Chemistry . 277 . 7 . 4601–4 . Feb 2002 . 11751925 . 10.1074/jbc.C100588200 . free .
• Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K . SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms . The Journal of Biological Chemistry . 275 . 13 . 9823–31 . Mar 2000 . 10734137 . 10.1074/jbc.275.13.9823 . free .
• Perin MS . Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin . Biochemistry . 35 . 43 . 13808–16 . Oct 1996 . 8901523 . 10.1021/bi960853x .

Notes and References

1. Craxton M . Genomic analysis of synaptotagmin genes . Genomics . 77 . 1–2 . 43–9 . Sep 2001 . 11543631 . 10.1006/geno.2001.6619 .
2. Web site: Entrez Gene: SYT9 synaptotagmin IX.
3. Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K . SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms . The Journal of Biological Chemistry . 275 . 13 . 9823–31 . Mar 2000 . 10734137 . 10.1074/jbc.275.13.9823 . free .
4. Haberman Y, Grimberg E, Fukuda M, Sagi-Eisenberg R . Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules . Journal of Cell Science . 116 . Pt 21 . 4307–18 . Nov 2003 . 12966166 . 10.1242/jcs.00719 . free .
5. Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A . Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity . The Journal of Biological Chemistry . 279 . 24 . 25665–72 . Jun 2004 . 15066994 . 10.1074/jbc.M311515200 . free .